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DNA’s unique structure enables the molecule to copy itself during cell division. When a cell prepares to divide, the DNA helix splits down the middle and becomes two single strands. These single strands serve as templates for building two new, double-stranded DNA molecules – each a replica of the original DNA molecule.
double helix
Deoxyribonucleic acid, more commonly known as DNA, is a complex molecule that contains all of the information necessary to build and maintain an organism. In other words, whenever organisms reproduce, a portion of their DNA is passed along to their offspring. …
DNA sequences are usually written in the 5′ to 3′ direction, meaning that the nucleotide at the 5′ end comes first and the nucleotide at the 3′ end comes last.
Genetic code is the term we use for the way that the four bases of DNA–the A, C, G, and Ts–are strung together in a way that the cellular machinery, the ribosome, can read them and turn them into a protein. In the genetic code, each three nucleotides in a row count as a triplet and code for a single amino acid.
DNA is often referred to as the code of life because it is just that: a code containing instructions on how to build various proteins. Other proteins work to protect and maintain the cell’s structure, move cargo around within the cell, or even help cells communicate with and signal to other cells.
Chromosomes are made of two DNA polymers that stick together via non-covalent hydrogen bonds. Chromosomal DNA consists of two DNA polymers that make up a 3-dimensional (3D) structure called a double helix.
The 3-dimensional double helix structure of DNA, correctly elucidated by James Watson and Francis Crick. Complementary bases are held together as a pair by hydrogen bonds.
The Genetic Code is stored on one of the two strands of a DNA molecules as a linear, non-overlapping sequence of the nitrogenous bases Adenine (A), Guanine (G), Cytosine (C) and Thymine (T). These are the “alphabet” of letters that are used to write the “code words”.
Characteristics of the Genetic Code
The genetic code consists of the sequence of nitrogen bases—A, C, G, U—in an mRNA chain. The four bases make up the “letters” of the genetic code. The letters are combined in groups of three to form code “words,” called codons. Each codon stands for (encodes) one amino acid, unless it codes for a start or stop signal.
four letters
A gene is the basic physical and functional unit of heredity. Genes are made up of DNA. Some genes act as instructions to make molecules called proteins. However, many genes do not code for proteins.
nucleic acids
The acidic component of DNA is its phosphate group, and the basic component of DNA is its nitrogenous base. Each nucleic acid monomer is made up of a sugar (deoxyribose in DNA), a nitrogenous base, and a phosphate group. The nitrogenous bases are called adenine (A), guanine (G), thymine (T), and cytosine (C).
Despite the fact that DNA does contain many basic groups, their basic properties are masked somewhat because of the fact that they hydrogen bond with each other to form base pairs. Hence it’s the acidic part of the molecule that dominates, and that is why we know DNA as an acid.
Because DNA is negatively charged, molecular biologists often use agarose gel electrophoresis to separate different sized DNA fragments when DNA samples are subjected to an electric field — due to their negative charge, all the DNA fragments will migrate toward the positively charged electrode, but smaller DNA …